TITLE:
Endovascular Repair for Abdominal Aortic Aneurysm Reduces Postoperative Blood Endotoxin Levels Assayed by the EAA Method Compared with Open Abdominal Surgery
AUTHORS:
Atsumi Ohishi, Satoshi Matsushita, Shizuyuki Dohi, Taira Yamamoto, Hirotaka Inaba, Kenji Kuwaki, Atsushi Amano
KEYWORDS:
Inflammation, Infection, Stents, Endovascular Aortic Repair
JOURNAL NAME:
World Journal of Cardiovascular Surgery,
Vol.4 No.6,
June
13,
2014
ABSTRACT: Introduction: We hypothesized to demonstrate whether there are significant differences in blood endotoxin (Et) levels after abdominal aortic surgery between endovascular aortic repair (EVAR) and open abdominal surgery. Methods: The patients who underwent the surgical treatment for abdominal aortic aneurysm were divided into two groups according to the procedures: open abdomen surgery (OP) and EVAR (SG). The value of Endotoxin Activity Assay (EAA) was compared between groups. Results: After surgery, Et level was significantly higher in the OP group than in the SG group on postoperative day 3. Neutrophil count was significantly higher in the OP group immediately after treatment, but no significant difference was seen thereafter. There were no differences between the groups in other inflammatory markers. Conclusions: This study indicated that EVAR was less invasive compared to an open abdominal surgery from the standpoint of assessing postoperative endotoxin activity (EA) levels measured by EAA.