TITLE:
Enzyme Kinetic Equations of Irreversible and Reversible Reactions in Metabolism
AUTHORS:
Santiago Imperial, Josep J. Centelles
KEYWORDS:
Adair Equation, Enzyme Kinetics, Equilibrium Constant, Haldane Relationship, Hill Equation, Metabolism, Michaelis Menten Equation, Reversible Reactions
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.2 No.4,
June
12,
2014
ABSTRACT: This paper compares the irreversible and
reversible rate equations from several uni-uni kinetic mechanisms (Michaelis-Menten,
Hill and Adair equations) and bi-bi mechanisms (single- and double- displacement
equations). In reversible reactions, Haldane relationship is considered to be
identical for all mechanisms considered and reversible equations can be also
obtained from this rela- tionship. Some reversible reactions of the metabolism
are also presented, with their equilibrium constant.