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Mahle, W.T., Fourshee, M.T., Naftel, D.M., Alejos, J.C., Caldwell, R.L., Uzark, K., Berg, A., Kanter, K.R. and Pediatric Heart Transplant Study Group (2009) Does CMV Serology Impact Outcome after Pediatric Heart Transplantation? The Journal of Heart and Lung Transplantation, 28, 1299-1305.

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• TITLE: Pulmonary Complications as a Cause of Death after Renal Transplantation

  AUTHORS: Ventsislava Pencheva, Daniela Petrova, Diyan Genov, Ognian Georgiev

  KEYWORDS: Fatal Outcome, Recipient, Immunosuppression

  JOURNAL NAME: Open Journal of Internal Medicine, Vol.4 No.2, June 11, 2014

  ABSTRACT: Objectives: To analyse the risk factors for death as a result of pulmonary complications in kidney transplant patients. Material and Methods: 267 patients after renal transplantation were prospectively studied. The kidney recipients were followed for the development of pulmonary complications and their outcome for a period of 7 years. Different noninvasive and invasive diagnostic tests were used in cases suspected for lung disease. Results: Risk factors for death as a result of pulmonary complications are development of lung diseases in the first six months after operation (P : 3.216; 95% CI: 1.067 - 5.577; P = 0.011). The factors associated with lower rate of fatal outcome are positive serology test for Cytomegalovirus of the recipient before transplantation (P = 0.034) and use of azathioprine (HR: 0.720; 95% CI: 0.526 - 0.986; P = 0.04). Conclusions: The risk factors may be used to identify patients at increased risk for death due to the pulmonary complications. Strictly monitoring of higher-risk patients can reduce the morbidity and mortality after renal transplantation.