TITLE:
Tumor Recurrence after Negative Pressure Wound Therapy: An Alert Call
AUTHORS:
Patricio Andrades, Manuel Figueroa, Sergio Sepúlveda, Susana Benitez, Cristian Erazo, Stefan Danilla
KEYWORDS:
Negative Pressure Wound Therapy, Vacuum Assisted Closure, Cancer, Recurrence
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.3 No.6,
June
11,
2014
ABSTRACT: In
this report, we present a 22-year-old patient with soft tissue sarcoma of the
lower extremity that developed wound dehiscence after
surgery. Biopsy demonstrated negative margins for cancer. He was treated with
negative pressure wound therapy for 6 weeks and started to present increased
wound exudates, local pain and proliferating tissue that was positive for tumor
recurrence. Consequently he underwent lower extremity amputation with hip
disarticulation by the orthopedic team. Although we cannot determine with
certainty a full causative relationship, it seems prudent to advise cautious
use of negative pressure wound therapy in oncologic related wound beds.