TITLE:
A Rare Cause of Pneumoperitoneum: Perforated Gastrointestinal Stromal Tumor (GIST)
AUTHORS:
Thukirtha Manoharan, Mahin Mohammadi, Orhan Bulut
KEYWORDS:
Gastrointestinal Stromal Tumor, GIST, Pneumoperitoneum, Perforation, Small Intestine
JOURNAL NAME:
Open Journal of Gastroenterology,
Vol.4 No.5,
May
23,
2014
ABSTRACT: Gastrointestinal stromal tumor (GIST) is the most
common mesenchymal tumor and has a malignant potential. The clinical
presentation with pneumoperitoneum and peritonitis is extremely rare. We report
a case of a 40-year-old male presented with symptoms of acute abdomen. Radiological
work-up confirmed pneumoperitoneum. Emergency laparatomy and complete resection
were performed. The final diagnosis revealed perforated GIST originating from
the jejunum. If an abdominal mass presents with pneumoperitoneum and
peritonitis, jejunal GIST should be considered in diagnosis. A complete radical
resection followed by postoperative adjuvant chemotheraphy with Imatinib is
recommended.