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Alec, B., Platt, M.D., Russell Localio, A., Colleen, M., Brensinger, M.S., Dean, G.C., Jason, D.C., Robert Gross, M.D., Catherine, S.P., Maureen Price, R.N., Joshua, P.M., Abigail, C., Craig, W.N., Brian, L.S., Mitchell, S.L. and Stephen, E.K. (2008). Risk Factors for Nonadherence to Warfarin: Results from the IN-RANGE Study. Pharmacoepidemiology and Drug Safety, 17, 853-860.

has been cited by the following article:

• TITLE: Compliant to Warfarin Therapy after Mechanical Heart Valve Replacement

  AUTHORS: Ragab S. Shehata, Ahmed A. Elassal, Ayman A. Gabal

  KEYWORDS: Warfarin, Compliant, Mechanical Valve, Replacement

  JOURNAL NAME: Open Journal of Thoracic Surgery, Vol.4 No.2, May 22, 2014

  ABSTRACT: Introduction: Effective anticoagulation depends on demographic factors, patient education, drug knowledge and compliance. The aim of our study is to determine the factors that influence compliance to warfarin in the mechanical valve patient population and its relationship with thrombo-embolic and bleeding events. Patients and Methods: 113 patients underwent mechanical valve replacement (Aortic, mitral or both) at King Abdul-Aziz University Hospital, from 2006 to 2012, patients divided into two groups according to warfarin compliant. Results: 113 patients reviewed in our study, 69 (61.1%) patients found compliant, 36 (31.9%) patients found non compliant, and 8 (7.1%) patients missed. The mean age for all patients was 39.25 y: 76 (67.3%) ware male, 37 (32.7%) were female. Mean age for compliant patients was 40.19 y versus 33.3 y for noncompliant patients with p value 0.017. Male patient less complaint than female with significant 0.01, the mean frequency of follow up was less (32.32 days) in compliant vs. (67.73 days) in non complaint patient. Conclusion: younger age, female gender, Arabic race, assistance at home, education, and single drug use are factors associated with patient compliant, non compliance are associated with higher mortality and valve related complication.