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Siddiqui, A.A., Yang, K., Spechler, S.J., Cryer, B., Davila, R., Cipher, D. and Harford, W.V. (2009) Duration of the Interval between the Completion of Bowel Preparation and the Start of Colonoscopy Predicts Bowel-Preparation Quality. Gastrointestinal Endoscopy, 69, 700-706.

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• TITLE: Colorectal Cancer Screening in a Spanish Town: Evaluation of Colonoscopy Preparation, Sedation by the Endoscopist and Screening Results

  AUTHORS: Rebeca Higuera Álvarez, Raquel González Monasterio, Fidencio Bao Pérez, Pablo Ruiz Eguiluz

  KEYWORDS: Colorectal Cancer Screening Preparation Sedation

  JOURNAL NAME: Open Journal of Gastroenterology, Vol.4 No.5, May 22, 2014

  ABSTRACT: Objective: The aim of this study is to evaluate the colonic cleansing preparation and colorectal cancer screening results in Sestao (Bilbao); and to verify the safety of endoscopist-controlled sedation. Materials and methods: A retrospective observational study of colorectal cancer screening using the immunological faecal occult blood test in a medium-risk population in this region, with colonoscopy being performed in the event of a positive result. The colonic cleansing preparation was administered in split doses; the second dose was administered 4 hours prior to colonoscopy. The quality of the preparation and lesion detection were evaluated. Sedation-related complications were analyzed. Results: Participation was high (4342 of 6896 people invited, 62.99%), with 309 subjects (7.12%) presenting a positive immunological faecal occult blood test. A high percentage of the 284 colonoscopies had optimal preparation: 276 (97.18%) had an adequate preparation. A total of 22 (7.91%) sedation-related complications were detected: only one (0.36%) was serious. A total of 140 high-risk adenomas were removed (47.13%) and 24 carcinomas were diagnosed (8.08%). Both these percentages are high. Conclusions: Split doses of colonoscopy preparation and reduction of the time interval between the second dose and the colonoscopy result in a high percentage of adequate preparation and lesion detection. Sedation by trained endoscopists is safe and effective. An immunological faecal occult blood test-based screening program is feasible and allows malignant and precancerous lesions to be efficiently detected and treated.