Article citationsMore>>
Jian, D., Jiang, D., Su, J., Chen, W., Hu, X., Kuang, Y., Xie, H., Li, J. and Chen, X. (2011) Diethylstilbestrol Enhances Melanogenesis via cAMP-PKA-Mediating Up-Regulation of Tyrosinase and MITF in Mouse B16 Melanoma Cells. Steroids, 76, 1297-1304.
http://dx.doi.org/10.1016/j.steroids.2011.06.008
has been cited by the following article:
-
TITLE:
Preliminary Colorimetric Assessment of Progressive Nonsegmental Vitiligo under Short-Term Intravenous Methylprednisolone Pulse Therapy
AUTHORS:
Yuiko Nagata, Atsushi Tanemura, Emi Ono, Aya Tanaka, Kenichi Kato, Mizuho Yamada, Ichiro Katayama
KEYWORDS:
Intravenous Methylprednisolone Pulse Therapy, Progressive Nonsegmental Vitiligo, Spectrophotometer
JOURNAL NAME:
Journal of Cosmetics, Dermatological Sciences and Applications,
Vol.4 No.3,
May
16,
2014
ABSTRACT: Although the
administration of systemic steroid for nonsegmental vitiligo in the progressive
stage is a recommended treatment according to guidelines, the clinical efficacy
of this regimen has not been fully established. In this study, we evaluated the
clinical efficacy of half-dose steroid treatment and stratified the evidence
regarding its usefulness in progressive vitiligo patients. Half-dose steroid
pulse therapy (500 mg/day of methylprednisolone for three sequential days) was
administered intravenously three times monthly in five vitiligo patients. The
visual changes in vitiligo lesions were evaluated on photographs and quantified
using a spectrophotometer. As results, all patients completed three cycles of
treatment without severe adverse events. Three of the five patients achieved
disease arrest with decrease in white contrast. Therefore, short-term and halfdose
steroid therapy is well tolerated and effective for achieving disease arrest in
progressive nonsegmental vitiligo. The whiteness assessed by a
spectrophotometer is possibly associated with therapeutic response to steroid
therapy.