TITLE:
Natural Products for the Treatment of Type 2 Diabetes Mellitus
AUTHORS:
Rupal Patel Mansukhani, Lucio R. Volino, Rozena Varghese
KEYWORDS:
Dietary, Supplements, Natural, Products, Diabetes
JOURNAL NAME:
Pharmacology & Pharmacy,
Vol.5 No.5,
May
13,
2014
ABSTRACT: In the past decade,
there has been an increase in the use of natural products in type 2 diabetes
mellitus (T2DM). Several agents, such as guar gum, magnesium, oat bran, blond
psyllium, and soy, have shown efficacy for treatment of T2DM. Objective: To review the scientific literature to identify effects of
natural products (i.e., dietary
supplements) for the treatment of T2DM. Methods: A search of Natural Medicines
Comprehensive Database was performed to identify natural products advocated
for the treatment of T2DM. Natural products categorized as both “possibly effective”
and “likely safe” (guar gum, magnesium, oat bran, blond psyllium, and soy) were
selected for review. A MEDLINE (1950-March 2013) literature review was
performed. Articles published within the last ten years (January 2003-March
2013) and pertinent articles published prior to 2003 were included in this
review. Diabetes prevention studies were not selected for this review. Conclusions: Based on the published information,
there is little evidence to support the use of herbal products for the
treatment of T2DM. Some agents may be useful as adjunctive therapy; however,
patients should be encouraged to speak with their health care practitioner
before starting or stopping any herbal products.