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Sanchez-Lozada, L.G., Tapia, E., Avila-Casado, C., Soto, V., Franco, M., Santamaría, J., et al. (2002) Mild Hyperuricemia Induces Glomerular Hypertension in Normal Rats. American Journal of Physiology. Renal Physiology, 283, F1105-F1110.
has been cited by the following article:
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TITLE:
The Nephrotoxic Impact of Oseltamivir in Male Albino Rats after Repeated Exposure
AUTHORS:
Falah Muosa Kadhim Al-Rekabi
KEYWORDS:
Olseltamivir, Nephrotoxic, Albino Rats, Repeated Exposure
JOURNAL NAME:
Pharmacology & Pharmacy,
Vol.5 No.5,
May
13,
2014
ABSTRACT: The effects of
oseltamivir administration, effectively against influenza viruses A and B, on
some selected parameters of rat kidney function were investigated to evaluate
its possible nephrotoxic effects. Eighteen (18) albino male Wistar rats with
body weights ranging from 150 - 190 g were divided into three groups, the
first group (T1) was treated orally with 1 mg/kg BW as a therapeutic dose of oseltamivir
for 7 consecutive days. The second group (T2) was treated with the same dose
for six weeks, while the control group was dosed with distilled water. The
results revealed a significant increase (P