TITLE:
Optimization of Exenatide plus Detemir Treatment for Morbid Obese Patients with Insulin Dependent Diabetes Resistant to Conventional Treatment. Effect of Exenatide on Patients with Mellitus Diabetes Type 2
AUTHORS:
Alfonso López Ruiz, María Ángeles Núñez Sánchez, Noelia Victoria García-Talavera Espín, Amparo Meoro Avilés, Cristina del Peso Gilsanz, Ricardo Soriano Sánchez, María Teresa Gallego García, José Soriano Palao, María Dolores Ortuño, Sacramento Tomás Navarro, Collaborative Groups of the Diabetes and Obesity Unit of the Hospital Reina Sofía
KEYWORDS:
Type 2 Diabetes Mellitus; Exenatide; Cardiovascular Risk; Physical and Biochemical Parameters
JOURNAL NAME:
Pharmacology & Pharmacy,
Vol.5 No.4,
April
23,
2014
ABSTRACT: The purpose of this study
was to analyze the effects of the treatment with Exenatide joint to insulin
detemir. The study was carried out with obese patients with type 2 diabetes
mellitus (DM2) and deficient control, despite intensive insulin therapy
combined with oral antidiabetics. A longitudinal study was made with 15
patients controlled by the Endocrinology and Nutrition Section of the Reina
Sofía University Hospital, Murcia. These patients were treated with Exenatide joint
to insulin during 3, 6 and 12 months. Statistically meaningful differences (p