TITLE:
Treatment of Nodal Non Hodgkin Lymphoma in West Africa: Experience of Institut Curie in Dakar
AUTHORS:
P. M. Gaye, A. A. Kassé, D. Diouf, M. M. Dieng, A. Dem
KEYWORDS:
Non Hodgkin Lymphoma, NHL, Africa
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.5 No.5,
April
28,
2014
ABSTRACT: In Senegal,
few studies have been devoted to non-Hodgkin’s lymphoma. We conducted a retrospective
descriptive study of 73 cases treated at the Institut J. Curie Hospital
Aristide Le Dantec for non-Hodgkin’s lymphomas from 2001 to 2007. The main objective was to determine the clinical and
therapeutic aspects. Our population consisted of 39 men and 34 women (sex
ratio: 1.14). The average age was 36 years with extremes of 5 and 76 years. The
most common locations were cervical (30.6%) and oropharynx (8.21%). Multiple
locations were found in 30.6% of cases. Only 54.4% have histological exam.
Patients were managed on cytology basis 42.6% of cases. Histology was performed
in 39 patients (54.4%). Among these patients, 69% had aggressive lymphoma, of
which 12.82% had a large B-cell lymphoma among indolent lymphomas (59%). The
small cleaved cell lymphoma was most often found with 78.26% of cases. The
patients were staged with insufficient tools. The protocol most often used was
CHOP (64.3%). The most common complications reported were gastrointestinal
(11%) followed by skin complications (8.2%). Radiotherapy was performed for 6
patients or 8.2% of cases. Therapeutic strategy was most often used as chemotherapy
alone (69.9%). The median duration of follow-up is 18 months.