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Margel, D., Urbach, D., Lipscombe, L.L., Bell, C.M., Kulkarni, G., Austin, P.C. and Fleshner, N. (2013) Association between Metformin Use and Risk of Prostate Cancer and Its Grade. Journal of National Cancer Institution, 105, 1123-1131.

has been cited by the following article:

• TITLE: Obesity, Diabetes Mellitus and Vascular Disease: A Complex Relationship with Prostate Cancer

  AUTHORS: Simona Di Francesco, Raffaele L. Tenaglia

  KEYWORDS: Prostate Cancer, Obesity, Diabetes Mellitus, Vascular Disease

  JOURNAL NAME: Journal of Cancer Therapy, Vol.5 No.5, April 23, 2014

  ABSTRACT: Background: Obesity, type II Diabetes mellitus (DMII) and vascular damage could be implicated in prostate cancer (PCa) nevertheless no clear results has been reached. The aim of the research was to investigate the association of these alterations with PCa at initial diagnosis, without the influence of hormone therapy or chemotherapy. Methods: Retrospective analysis of 400 patients undergoing prostate biopsy at our institution between 2005 and 2012 was conducted. We examined associations of obesity, DMII and vascular damage in 200 patients with PCa diagnosis versus 200 age-matched controls. Men with history of hormone therapy or chemotherapy, prostate or bladder surgery were excluded. Results: Obesity was significantly associated (OR 2.10, p