TITLE:
Exenatide Response in an Adolescent’s Morbid Obesity
AUTHORS:
Ricardo Soriano Sánchez, Alfonso López Ruiz, M. Ángeles Núñez Sánchez, Noelia Victoria García-Talavera Espín, Amparo Meoro Avilés, María Teresa Gallego García, Cristina del Peso Gilsanz, José Soriano Palao, Collaborative Groups of the Diabetes Obesity Unit of the Hospital Reina Sofía
KEYWORDS:
Type 2 Diabetes Mellitus; Exenatide; Adolescent; Obestity
JOURNAL NAME:
Pharmacology & Pharmacy,
Vol.5 No.4,
April
23,
2014
ABSTRACT: Adolescent
obesity is a health problem worldwide. Drug therapy for obesity in children is
only acceptable if done within the framework
of a comprehensive weight loss, prevention of comorbidities, including
health education, changes in lifestyles, diet and exercise. These
pharmacological treatments indicate that mainly young patients did not respond to
standard measures and developing complications. The role of bariatric surgery,
with or without the use of drugs is subject to further research to elucidate
its role among the various treatment options for these patients. Currently
being studied a wide range of drugs to those included gastrointestinal
hormones. Scientific information regarding the use of exenatide in obese
patients without diabetes is still limited. The use of exenatide in adolescents
with morbid obesity may represent a therapeutic complement invaluable,
effective and free of complications, and prevents future
bariatric surgery.