TITLE:
Mandibular Fibrosarcoma and Bile Duct Adenoma in a Pet Rabbit (Oryctolagus cuniculi): A Case Report
AUTHORS:
Inge Thas, Gerry M. Dorrestein, Nathalie Ariel Cohen-Solal
KEYWORDS:
Bile Duct Adenoma, Facial Swelling, Fibrosarcoma, Mandible, Rabbit
JOURNAL NAME:
Open Journal of Pathology,
Vol.4 No.2,
April
22,
2014
ABSTRACT: This report describes the clinical manifestations and pathological findings
in a 4-year-old neutered male dwarf rabbit diagnosed with a mandibular
fibrosarcoma. The rabbit was evaluated for a unilateral mandibular swelling and
an acute onset of oral blood loss. Physical examination confirmed a marked
facial asymmetry with a swollen painful left mandible. Radiographic projections
of the skull revealed a left mandibular mass extending into the oral cavity.
Tissue biopsies demonstrated severe bone destruction and a presumptive
pathological diagnosis of a mandibular osteosarcoma were made. A helical CT
(computed tomography) study of the skull confirmed the severe mandibular bone
destruction and the oral extension of the mass. The patient was treated
palliative with oral meloxicam and subcutaneous penicillin injections. Six months
later, the rabbit died in a natural way. Postmortem examination led to final
diagnosis of severe left facial malformation due to mandibular fibrosarcoma. A
bile duct adenoma was found in the liver. To the author’s knowledge, this is
the first description of a spontaneous mandibular fibrosarcoma in a pet rabbit.