TITLE:
Iron Status of Multiple Transfused Sickle Cell Anaemia Patients Attending a Sickle Cell Clinic in Benin City, Nigeria
AUTHORS:
A. I. Ikusemoro, N. K. D. Halim, O. A. Awodu, F. A. Ehiaghe, E. M. Isoa, I. J. Ehiaghe
KEYWORDS:
Sickle Cell Anaemia, Multiple Transfusions, Serum Ferritin, Enzyme Linked Immuno Sorbent Assay
JOURNAL NAME:
Open Journal of Pathology,
Vol.4 No.2,
April
22,
2014
ABSTRACT: This study was aimed at
evaluating the iron status of multiple blood transfused sickle cell anaemia
(SCA) patients in Benin City, Nigeria. A total of 86 subjects participated in
the study, comprising of 30 multiple transfused SCA subjects, 30 of rarely
transfused SCA subjects and 26 of age and sex matched healthy control subjects.
Serum ferritin was determined by enzyme linked immuno sorbent assay technique.
Serum iron and Total iron binding capacity was determined by spectrophometric
method. The mean serum ferritin concentration was elevated in the sickle cell
anaemia patients whose multiple transfusions (MT) are more than those who were
rarely transfused (RT) as compared with the control groups (p