TITLE:
The Effectiveness of Surgical Methods of Treatment of Pulmonary Tuberculosis for Patients with Multidrug Resistant at Adequate Chemotherapy (Retrospective, Case Control, Comparative Research)
AUTHORS:
Kulakhmet Dildakhmetovich Yerimbetov, Askar Shintasovich Zetov, Tleukhan Abildayev, Gulbadan Sabitovna Bekembayeva, Shahimurat Shaimovych Ismailov
KEYWORDS:
Surgical Treatment, Drug Resistance, Chemotherapy
JOURNAL NAME:
Surgical Science,
Vol.5 No.4,
April
21,
2014
ABSTRACT: In this article, there are given results of comparative studying of
efficiency of surgical and conservative treatment of 277 patients with
multidrug resistant tuberculosis. The effectiveness of the surgical treatment
of the main group of patients against the background of chemotherapy with anti-TB
chemotherapy with the drugs of the reserve line has been compared with two
control groups: Group I—Surgical intervention was implemented with drugs of the
first line, Group II—Chemotherapy was conducted with anti-TB drugs of the
second line without surgical intervention. Treatment outcomes in three groups
were stated after cohort investigation, and following results were obtained: Effectiveness
of surgical treatment of patients of the main group with MDR TB treated with
anti-TB drugs of the second line constituted 98.0% versus 53.7% in the Group
II. Effectiveness of conservative treatment of patients in III (control) Group
constituted 74.4%. Analysis of results obtained showed that the outcomes in the
main group after regimen completed were higher by 1.8 times than in patients
operated against the background of treatment with the drugs of the first line
and by 1.3 times higher than effectiveness in patients in the Group III (P