TITLE:
Influence of Surgical Technique on Overall Survival, Disease Free Interval and New Lesion Development Interval in Dogs with Mammary Tumors
AUTHORS:
Rodrigo dos Santos Horta, Gleidice Eunice Lavalle, Rúbia Monteiro de Castro Cunha, Larissa Layara de Moura, Roberto Baracat de Araújo, Geovanni Dantas Cassali
KEYWORDS:
Female Dog, Mammary Neoplasms, Mastectomy
JOURNAL NAME:
Advances in Breast Cancer Research,
Vol.3 No.2,
April
17,
2014
ABSTRACT: The best surgical
technique for the treatment of mammary tumors in female dogs has been
exhaustively debated among the scientific community. Despite biological
knowledge of these tumors, some
authors have suggested aggressive procedures, without any clinical advantage.
The aim of this study was to evaluate the influence of surgical procedure on
the overall survival, disease-free interval and new lesion development interval
in dogs with mammary tumors treated according
to established prognostic factors. This prospective study included 143 intact
female dogs that underwent
surgery for mammary neoplasms and were followed up for about 738.5 days. Each animal represented a repetition.
Each surgical technique represented a group: lumpectomy (P1), mammectomy (P2),
regional mastectomy without cranial abdominal gland involvement (P3), regional mastectomy with cranial
abdominal gland involvement (P4), and radical mastectomy (P5). Considering only
the first surgical event, 84.6% of animals had more than one mammary tumor, and
tumors were identified in two mammary chains in 52.5%. There was no difference
in ipsilateral and contralateral tumor development when surgical techniques
were compared. Only 33 dogs
developed new lesions in remaining mammary tissue, without correlation with
primary lesion. Surgical technique had no effect on the overall survival,
disease-free interval and new
lesion development interval in patients on this study, which respected
oncological surgery principles and established prognostic factors for mammary
gland tumors in dogs.