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Curatolo, M., Arendt-Nielsen, L. and Petersen-Felix, S. (2006) Central Hypersensitivity in Chronic Pain: Mechanisms and Clinical Implications. Physical Medicine & Rehabilitation Clinics of North America, 17, 287-302.

has been cited by the following article:

• TITLE: Pain Hypersensitivity: A Bio-Psychological Explanation of Chronic Musculoskeletal Pain and Underpinning Theory

  AUTHORS: Zakir Uddin, Joy C. MacDermid

  KEYWORDS: Abnormal Pain, Theory, Sensitivity

  JOURNAL NAME: Pain Studies and Treatment, Vol.2 No.2, April 15, 2014

  ABSTRACT: Hypersensitivity is a phenomenon that has a dual role: adaptive (protective) and maladaptive (pathological) based on different aspects of the pain mechanism. The mechanism of hypersensitivity has not been fully defined. However, it is known that over-excitability (too much sensitivity) of neurons can arise in both peripheral and central components of the nervous system. Pain theories can be useful in helping to explain complex phenomenon like hypersensitivity. The Gate control theory and other more bio-psychological pain models may assist us to understand a mechanism of chronic musculoskeletal pain. This article discusses a mechanism based pain model.