TITLE:
Emerging Trends in the Etiology and Antimicrobial Susceptibility Pattern of Enteric Pathogens in Rural Coastal India
AUTHORS:
Mamatha Ballal, Suganthi M. Devadas, Rituparna Chakraborty, Vignesh Shetty
KEYWORDS:
Diarrheogenic Escherichia coli (DEC), Salmonella, Shigella, Vibrio, Multidrug Resistant
JOURNAL NAME:
International Journal of Clinical Medicine,
Vol.5 No.7,
April
14,
2014
ABSTRACT: Introduction: Gastroenteritis is recognized as a serious
public health problem in India. It is a syndrome that can be caused by
different bacterial, viral and parasitic pathogens. Indiscriminate use of
antibacterial agents has resulted in the development of multidrug resistant
organisms. A retrospective study was done to analyze the etiological spectrum
of diarrhoea and to determine the antimicrobial resistance pattern of bacterial
pathogens. Methodology: Fecal specimens from patients with acute or chronic
diarrhoea were received prior antibiotic administration and processed for
routine microscopy of parasites; culture, antimicrobial susceptibility testing
and polymerase chain reaction for bacterial pathogens and latex agglutination
for rotavirus. Results: Out of the 6043 stool samples collected during the period
of Jan 2005-Dec 2013, 678 (11.2%) enteric pathogens were isolated. The
predominant isolates were Diarrheagenic
Escherichia coli (DEC) (46.3%)
followed by Salmonella, Shigella, Vibrio cholerae and parasites. Certain unusual pathogens were also
isolated. Among age wise distribution, Diarrheagenic
Escherichia coli (DEC) mainly Enteroaggregative
Escherichia coli (EAEC) was isolated from