TITLE:
Effect of Carbohydrate Intolerance and Gestational Diabetes on Obstetric and Perinatal Outcomes
AUTHORS:
Leticia Lara-Ávila, José Manuel Brambila-Durán, Diego Armando Camacho-Ramírez, Felipe de Jesús Peraza-Garay, Adrián Herrera-Salazar, Fred Morgan-Ortiz
KEYWORDS:
Glucose Tolerance Test; Carbohydrate Intolerance; Gestational Diabetes; Perinatal Outcome
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.4 No.6,
April
2,
2014
ABSTRACT: Objectives: To compare the
frequency of obstetric and perinatal complications among patients with
carbohydrate intolerance (CHI) and gestational diabetes (GD). Materials and
Methods: In a prospective study at the Civil Hospital of Culiacán, we studied
182 pregnant patients between 16 and 30 weeks of gestation (WG) who received a
glucose tolerance test following the oral administration of 100 g of glucose.
The patients were classified as normal (n = 53), CHI (n = 61) and GD (n = 68) between January 15 to November
30, 2012. The analyzed variables included the frequency of polyhydramnios,
preeclampsia-eclampsia, obstetric hemorrhage, fetal macrosomia, and admission
to a neonatal intensive care unit (NICU). Results: No significant differences
were found between women with CHI and women with GD with respect to obstetric
hemorrhage (P = 0.774),
preeclampsia-eclampsia (P =
0.590), and macrosomia (P =
0.119). However, polyhydramnios was more frequent in CHI group (OR = 3)
compared to GD, whereas admission to the NICU was lower in the CHI group
compared to GD group (OR = 0.38). Conclusion: Preeclampsia-eclampsia, obstetric
hemorrhage, and macrosomia were similar among patients with CHI and GD. In contrast,
polyhydramnios was more frequent in patients with CHI compared to patients with
GD, but admission to the NICU was more frequent in patients with GD.