TITLE:
Characterization and Utilization of Starches Extracted from Florencia and Waxy Maize Hybrids for Tablet Formulation: Compaction Behaviour and Tablet Properties
AUTHORS:
Anikó Szepes, Piroska Szabó-Révész, János Bajdik, Péter Kása Jr., Miklós Neményi, Roland Pap, Attila József Kovács, Klára Pintye-Hódi
KEYWORDS:
Maize Starch; Micromeritics; X-Ray Diffraction; Compression Behaviour; Tablets
JOURNAL NAME:
American Journal of Plant Sciences,
Vol.5 No.6,
March
24,
2014
ABSTRACT: The aim of this work is to analyze the
particle characteristics, such as shape, roundness and size, of starches
extracted from Florencia and waxy maize hybrids. The micromeritics and
structural properties of the samples were examined. The evaluation of flow
properties, densification and compression behaviour of the powders was carried
out. Physical parameters and swelling characteristics of tablets containing
Florencia and waxy maize starch were also studied. Starch samples were compared
with respect to their applicability as excipients in tablet formulation. The
samples exhibited identical structure and similar particle characteristics.
Maize starch extracted from the Florencia dent hybrid showed better flowability
and compressibility in tableting experiments, which resulted in better
mechanical tablet properties. With regard to utilization as a disintegrant,
Florencia starch indicated rapid and intensive swelling and proved to act more
effectively in the swelling process than waxy maize starch.