TITLE:
Internal environment for growth of cancer cells in mice: hypothermia, anemia and lymphocytopenia
AUTHORS:
Mayumi Watanabe, Hiroaki Matsumoto, Chikako Tomiyama, Kohei Akazawa, Toru Abo
KEYWORDS:
Cancer; Hypothermia; Anemia;
Immunosuppression; Glycolysis; Mitochondria
JOURNAL NAME:
Health,
Vol.3 No.4,
April
29,
2011
ABSTRACT: The internal environment in tumor-bearing mice was investigated in detail. When EL-4 lymphoma cells (5 × 106 cells/mouse) were intraperitoneally inoculated into C57BL/6 mice, approximately 70% of the mice died by day 24. In this regard, the internal environment was compared between control mice, surviving mice and tumor-bearing mice which died. The most prominent sign was hypothermia (