TITLE:
Socioeconomic Indices Performance for HIV Diagnostic on Severely Malnourished Children in Burkina Faso
AUTHORS:
Léon G. Blaise Savadogo, Philippe Donnen, Michèle Dramaix
KEYWORDS:
Socioeconomic Indices; Test Performance; HIV; Severely Malnourished Children
JOURNAL NAME:
World Journal of AIDS,
Vol.4 No.1,
March
21,
2014
ABSTRACT: Children living with HIV should be diagnosed
as early as possible and linked to antiretroviral treatment. The costs of HIV
virological testing, individual and social implications of the disease require
critical quality of the medical approach to diagnostic strategy. Socioeconomic
data can be used to refine the medical decision. The objective of this analysis
was to determine informative capacity of socioeconomic indices in the diagnosis
and approach of HIV in severely malnourished children using receiver operating
characteristic (ROC) curves. Materials and Methods: This was a test performance
analysis conducted from data of severely malnourished children at an inpatient
feeding therapeutic center in Ouagadougou. Anthropometric and social indices
have been used as tests; their
sensitivity, specificity and predictive values have been calculated. ROC curves
and areas under curves were obtained. Medical decision aid scheme has been
validated from severely malnourished children data. Results: Socioeconomic
indices showed high performance to discriminate severely malnourished HIV
infected and uninfected children, with high area under ROC curves. The medical
decision aid scheme specificity reached 97.6% with predictive values close to
85%. Conclusion: This approach can help for expanding ART for children in low
income countries and achieve the maximum ART benefits in child socioeconomic
kneed context.