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Halder R.C., Seki S., Weerasinghe A., Kawamura T., Watanabe H. and Abo T. (1998) Characterization of NK cells and extrathymic T cells generated in the liver of irradiated mice with a liver shield. Clinical and Experimental Immunology, 144, 434-447. doi:10.1046/j.1365-2249.1998.00726.x

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• TITLE: Internal environment for growth of cancer cells in mice: hypothermia, anemia and lymphocytopenia

  AUTHORS: Mayumi Watanabe, Hiroaki Matsumoto, Chikako Tomiyama, Kohei Akazawa, Toru Abo

  KEYWORDS: Cancer; Hypothermia; Anemia; Immunosuppression; Glycolysis; Mitochondria

  JOURNAL NAME: Health, Vol.3 No.4, April 29, 2011

  ABSTRACT: The internal environment in tumor-bearing mice was investigated in detail. When EL-4 lymphoma cells (5 × 106 cells/mouse) were intraperitoneally inoculated into C57BL/6 mice, approximately 70% of the mice died by day 24. In this regard, the internal environment was compared between control mice, surviving mice and tumor-bearing mice which died. The most prominent sign was hypothermia (