TITLE:
Signet Ring Cell Carcinoma of Ampulla of Vater: Report of a Rare Malignancy and Literature Review
AUTHORS:
Ihsane Souaf, Kawtar Znati, Sanae Chahbouni, Imane Hafid, Hassania Ameurtesse, Nawale Hammas, Leila Chbani, Hinde El Fatemi, Tawfik Harmouch, Afaf Amarti
KEYWORDS:
Ampulla of Vater; Carcinoma; Signet Ring Cell; Pancreas
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.3 No.3,
March
13,
2014
ABSTRACT: Introduction: Signet ring cell carcinoma is a
rare tumor that generally originates in the gastrointestinal tract. Signet-ring cell carcinoma of
the ampulla of Vater is extremely uncommon and a very rare clinical entity, which is infrequently
reported in medical literature and only 31 cases have been mentioned. Most
tumors affecting Vater’s Ampulla are adenocarcinomas and other histological variants are less frequent. It mainly
occurs in elderly patients. Case Presentation: We report a case of signet ring
cell carcinoma of Vater’s Ampulla. The tumour had infiltrated the duodenal, but
local lymph nodes were clear (T3N0M0). Duodenopancreatectomy with pylorus
preservation is the treatment of choice. Conclusions: Etiology and survival are not well-defined in the literature due to the
extreme rarity of this disease.