Article citationsMore>>

Romano, A., Gaeta, F., Valluzzi, R.L., Caruso, C., Rumi, G. and Bousquet, P.J. (2010) IgE-Mediated Hypersensitivity to Cephalosporins: Cross-Reactivity and Tolerability of Penicillins, Monobactams, and Carbapenems. Journal of Allergy and Clinical Immunology, 126, 994-999. http://dx.doi.org/10.1016/j.jaci.2010.06/052

has been cited by the following article:

• TITLE: Aztreonam Cell Mediated Hypersensitivity Cross Reactivity with Beta Lactam Antibiotics: The Possibility That It Exists

  AUTHORS: Ryan Urbas, Raxitkumar Patel, Arka Banerjee

  KEYWORDS: Piperacillin; Aztreonam; Cross; Reactivity; Allergy; Amoxicillin; Drug; Rash; Exanthem; Penicillin; Beta; Lactam; Cephalosporin; IgE; Maculopapular Rash

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.3 No.3, March 6, 2014

  ABSTRACT: A 61-year-old female with past medical history of maculopapular rash reaction to ciprofloxacin and amoxicillin being treated for diverticulitis develops the same rash with administration of piperacillin/tazobactam and aztreonam. A diffuse maculopapular rash developed after the administration of piperacillin. It resolved with discontinuation of the drug and the patient was switched to aztreonam and a very similar rash developed subsequently. In a review of the literature, there are no documented cases of a patient with an allergy to both aztreonam and piperacillin/tazobactam despite in vivo cross-reactivity. Unfortunately, there are no standardized allergy tests for aztreonam or piperacillin. This case, however, does offer the possibility that aztreonam may not always be the right alternative to persons with beta-lactam antibiotic allergies.