TITLE:
Diffusion-Weighted MR Imaging of the Benign Hepatic Focal Lesions
AUTHORS:
Adel El-Badrawy, Germeen Albair Ashmallah, Ahmed Mohamed Tawfik, Sherif Abdelfattah, Manal Salah-Eldin, Emad Eldin Azmy, Amro Awad El-Karef, Ghada A. Salem, Omar Farouk
KEYWORDS:
Diffusion; MR Imaging; Apparent Diffusion Coefficient; Benign Hepatic Focal Lesion
JOURNAL NAME:
Open Journal of Radiology,
Vol.4 No.1,
March
6,
2014
ABSTRACT: Purpose: To
determine the role of diffusion weighted MR imaging and apparent diffusion coefficient (ADC) in benign hepatic focal lesions. Method and Materials:
This study included 47 patients (29 M, 18 F with mean age of 43 years) with benign hepatic focal lesions. They were cyst (n = 8), hemangioma (n = 23), abscess (n = 5), adenoma (n = 5), focal nodular
hyperplasia (n = 4) and nodular regenerative hyperplasia (n = 2). They underwent
routine MR imaging and diffusion MR weighted imaging using 1.5 tesla MR unit (Symphony-Siemens). Diffusion MR imaging was done
using spin echo type of single shot echo planar imaging (EPI) with b value of
0, 500 & 1000 sec/mm2. The apparent diffusion coefficient (ADC)
map was reconstructed and ADC value was measured. The mean ADC values
correlated with histo-pathological results as well as follow-up imaging
results. Results: Adequate ADC
maps were obtained in 47 patients. The mean ADC values were 3.4 ± 0.12 × 10-3 mm2/sec in cystic lesion, 2.23 ± 0.08 × 10-3 mm2/sec in hemangioma, 1.94 ± 0.05 × 10-3 mm2/sec
in abscess, 1.72 ± 0.07 × 10-3 in focal nodular hyperplasia, 1.65 ± 0.06 × 10-3 mm2/sec
in adenoma, 1.62 ± 0.07 × 10-3 mm2/sec in nodular regenerative
hyperplasia. The mean ADC values were significantly different within benign
hepatic focal lesions (P