TITLE:
The Role of Pharmacists in Perioperative Antibiotic Application in a Hospital of Traditional Chinese Medicine (TCM)
AUTHORS:
Ruifang Xie, Zhicheng Li, Lingqi Zhu, Yun Zhang, Jie Shen, Xin Zhou
KEYWORDS:
Adherence; Perioperative Antibiotic Application; Intervention
JOURNAL NAME:
Pharmacology & Pharmacy,
Vol.5 No.3,
March
4,
2014
ABSTRACT: Objective: To determine adherence
to Chinese guidelines for perioperative antibiotic use in our hospital of TCM
and discuss the role of pharmacists on antibiotic management. Methods: 2844
operative cases between May 2011 and December 2011 in our hospital were
investigated by pharmacists and relative data were collected, including
demographic data, type of surgery, wound classification (clean and clean
contaminated) and parameters of antibiotic application (antibiotic choice,
route, dose, time of first dose, time of operative re-dosing and duration of
prophylaxis). The rationality of antibiotic administration in these cases was
respectively evaluated based on Chinese guidelines for perioperative antibiotic
use. Results: After intervention of pharmacists, perioperative antibiotic
application in our hospital was obviously improved from May to December of
2011: the rates of antibiotic application in operative cases and antibiotic
prophylaxis in clean operation were both decreased. However, there was no
significant improvement for the rate of rationality. In detail, TCM surgery was
well compliant with the guidelines: the rate of antibiotic application was less
than 30%, regimen of antibiotic prophylaxis and therapy was reasonable; in the
breast ward, antibiotic application was improved after pharmacists’ intervention: the rate
of antibiotic prophylaxis in clean operation significantly decreased from 100%
to 30%; however, in the anorectal ward, some troubles were resolved while other
new problems came out; in other ward such as general surgery and orthopedics,
old problems still existed. Conclusions: Protocol violations were frequent to
perioperative antibiotic application in our hospital due to considerable over
prescription. Intervention was effective but not enough. Further educational
strategies are essential for reducing costs and antibiotic resistance rates.