TITLE:
The 5 Hallmarks of Biomaterials Success: An Emphasis on Orthopaedics
AUTHORS:
Dustin L. Williams, Brad M. Isaacson
KEYWORDS:
Biomaterials; Orthopaedics; Implant; Bone; Biofilm
JOURNAL NAME:
Advances in Bioscience and Biotechnology,
Vol.5 No.4,
February
28,
2014
ABSTRACT: Over the past 200 years, there has been significant advancements in the
fields of bioengineering and orthopaedics. Investigators, clinicians and manufactures are learning that the success of implant systems is not limited to a single factor, but a combination of variables that
must work in unison to provide stability and high survivorship. Innovations
continue to advance these fields and include: biomimetic alterations,
three-dimensional, patient-specific reconstructions and novel coatings to
mitigate aseptic loosening or other pathologies. However, implant systems
continue to fail in clinical practice since they do not adhere to key
fundamental principles. Therefore, this article is intended to highlight 5
hallmarks of biomaterials that should be considered during design, surgery,
and post-operative rehabilitation.