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Lamarche, B., Uffelmann, K.D., Carpentier, A., Cohn, J.S., Steiner, G., Barrett, P.H. and Lewis, G.F. (1999) Triglyceride enrichement of HDL enhances in vivo metabolic clearance of HDL apo A1 in healthy men. Journal of Clinical Investigation, 103, 1191-1199.
http://dx.doi.org/10.1172/JCI5286
has been cited by the following article:
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TITLE:
Women with overweight, mixed hyperlipidemia, intolerance to glucose and diastolic hypertension
AUTHORS:
Ruth-Maria Korth
KEYWORDS:
Combined Telemedical Care; Overweight; Mixed Hyperlipidemia; Intolerance to Glucose; Hypertension; Renal Endothelium; Dyslipidemia; Women’s Health
JOURNAL NAME:
Health,
Vol.6 No.5,
February
27,
2014
ABSTRACT: Primarily healthy women who attended a practice of General Medicine were examined and coded data were evaluated using two statistical methods (n = 248, aged 36 ± 14 years). It was found that participants with LDL-related (mixed) hyperlipidemia showed higher blood pressure, a higher proportion of alcohol problems and/or smoking compared to normolipidemic women (p ≤ 0.05). These hyperlipidemic women who reported alcohol problems and/or smoking more often showed proteinuria and/or hematuria, rise of LDL/HDL, critical fasting blood glucose and lower HDL-cholesterol compared to hyperlipidemic women reporting healthy lifestyle (p ≤ 0.05). Likewise, high triglycerides were associated with rise of blood pressure and intolerance to glucose (p ≤ 0.05) and also with elevated total cholesterol. Alcohol-related hypertriglyceridemia overlapped with diastolic hypertension, rise of body weight and urine pathology, lowering of HDL-cholesterol and critical fasting blood glucose. The motivating message was that women with mixed hyperlipidemia and healthy lifestyle had functionally renal endothelium and healthy HDL-related baseline measures. Altogether, LDL-related hyperlipidemia and/or high triglycerides were correlated with diastolic hypertension whereby critical alcohol consumption declined renal endothelium and lowered HDL-cholesterol implicating baseline strategies to neutralize early risk factors.