TITLE:
Prevalence rates and cardiometabolic determinants of diabetes mellitus and pre-diabetes with projected coronary heart disease at bank site of Brazzaville
AUTHORS:
Gombet Thierry, Longo-Mbenza Benjamin, Ellenga-Mbolla Bertrand, Ikama M. Stephan, Kimbally-Kaky Gisèle, Nkoua Jean-Louis, Nge Okwe Augustin
KEYWORDS:
Workplace; Diabetes Mellitus Pre-Diabetes; Cardiovascular Risk; Brazzaville
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.4 No.2,
February
25,
2014
ABSTRACT: Background:
Aim: Congolese Bank employees are often inactive without valid information on
the burden of dysglycemia and cardiometabolic risk. This study aims to assess
the prevalence rates of diabetes mellitus (DM) and pre-diabetes and to identify
the environmental, genetic and cardiometabolic risk factors associated with Type
2 diabetes mellitus (T2DM) and pre-diabetes among Congolese bank employees. Methods:
In representative 126 bank employees from Brazzaville, Congo, Central Africa,
Abdominal obesity, dyslipidemia and metabolic syndrome (MetS) were defined by
IDF for Europe, NCEP-ATPIII and IDF criteria modified for Central Africa.
Projected high 10-year total risk of
coronary heart disease (CHD) ≥20% was calculated using Framingham
scores. Results: Out of the employees, 16% and 21.4% had DM and pre-diabetes,
respectively. The rate of T2DM among diabetics was estimated 90%. Aging, high
total cholesterol, high LDL-cholesterol, high conicity index and longer urban
residence after migration were significantly associated with pre-diabetes.
Physical inactivity, smoking, excessive alcohol intake, abdominal obesity,
female gender, low HDL-C, hypertension, CHD, projected high 10-year total CHD
risk, age ≥ 55 years, urban residence, Southern area residence, high socioeconomic status, non married status, MetS/NCEP, MetS/IDF for Europe and MetS/IDF for Africa were significantly associated with T2DM.MetS/IDF for Africa was the only independent determinant of T2DM. Conclusion: Urgent prevention and intervention programme are
needed to curb the alarming increase in DM, T2DM, pre-diabetes.