TITLE:
The Detectability for the Myocardial Fibrosis by Tagging Imaging on Cardiovascular Magnetic Resonance
AUTHORS:
Atsushi K. Kono, Pierre Croisille, Tatsuya Nishii, Katsusuke Kyotani, Koya Nishiyama, Mayumi Shigeru, Sachiko Takamine, Sei Fujiwara, Kazuro Sugimura
KEYWORDS:
Tagging Imaging; Late Gadolinium Enhancement; Myocardial Fibrosis; Cardiovascular Magnetic Resonance
JOURNAL NAME:
Open Journal of Radiology,
Vol.4 No.1,
February
18,
2014
ABSTRACT: Purpose: Myocardial fibrosis causes cardiac dysfunction,
arrhythmias, and sudden death. Tagging imaging on cardiovascular MR can measure
the intra-myocardial motion from the dynamic deformation of lines superimposed
on the myocardium. The purpose of this study was to evaluate the detectability
of myocardial fibrosis using tagging imaging and to compare this with conventional
cine imaging. Materials and Methods: We reviewed 4 normal control (NML)
subjects, 4 patients with myocarditis (MYO), and 4 patients with old myocardial
infarction (ICM). We measured circumferential strain (Ecc) from tagging
imaging, and regional wall thickening (rWT) from cine imaging. Fibrosis was
determined from a late gadolinium enhancement (LGE) image. We evaluate
diagnostic performance by comparing values of the area under curve (AUC) using
ROC analysis. Results: Mean values of Ecc and rWT decreased in the area of LGE
both in MYO and ICM patients. AUC values of Ecc and rWT in all subjects were
0.98 and 0.84, respectively (p