TITLE:
A case of sarcoidosis associated with chronic eosinophilic pneumonia
AUTHORS:
Halil Yanardag, Cuneyt Tetikkurt, Aslı Sezgin, Ertuğrul Oruc, Muammer Bilir
KEYWORDS:
Sarcoidosis; Chronic Eosinophilic Pneumonia; Pulmonary Eosinophilia
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.3 No.2,
February
12,
2014
ABSTRACT: A 78-year-old woman was referred to our university hospital due to dry
cough, fever, and weight loss. Laboratory revealed blood eosinophilia, high
ESR, CRP and LDH. Rheumatologic markers were negative. Chest X-ray showed
ground glass opacities in upper lobes. Uveitis developed in the left eye 1 week
after admission. Thorax CT revealed ground glass opacities, reticular appearence in the upper lobes, enlarged
axillary and mediastinal lymph nodes. Bronchoalveolar
lavage CD4/CD8 was 2.1 and had 48% eosinophils.
Histopathologic examination revealed eosinophilic infiltration and non-caseating epitheloid granulomas in the lung and mediastinal lymph nodes without
vasculitis. Symptoms, blood eosinophilia and initial thorax CT findings
improved after two months of methylprednisolone treatment. Chronic eosinophilic
pneumonia is a rare disease characterized by systemic and pulmonary
manifestations. It may be associated with other diseases.