TITLE:
Intravitreal Bevacizumab with Grid Photocoagulation for Recurrent Macular Edema Secondary to Retinal Vein Occlusion
AUTHORS:
Salah M. Mady, Asaad A. Ghanem
KEYWORDS:
Bevacizumab; Grid Laser Photocoagulation; Macular Edema; OCT; RVO
JOURNAL NAME:
Open Journal of Ophthalmology,
Vol.4 No.1,
February
10,
2014
ABSTRACT: Purpose: To assess the efficacy of intravitreal bevacizumab (IVB)
combined with grid photocoagulation in the management of recurrent macular
edema secondary to retinal vein occlusion (RVO). Methods: This is a prospective, non-randomized, interventional study. Thirty five eyes with
branch retinal vein occlusion (BRVO) and 15 eyes with central retinal vein
occlusion (CRVO) were treated with grid photocoagulation combined with IVB for
recurrent macular edema. The visual acuity, central macular thickness and intraocular pressure were outcome measures.
The mean duration of follow-up was 18.1 ± 3.6 months.
Results: One month after treatment, 45 of the 50 eyes showed complete resolution
of the cystoid space. Compared with initial values, final central macular thickness was reduced significantly in both BRVO and CRVO groups (P P = 0.012). The total number of IVB was 1.8 ± 0.3 for eyes with either BRVO or
CRVO. Conclusion: IVB combined with grid photocoagulation is an effective
treatment for reducing recurrent macular edema associated with RVO.