TITLE:
Feasibility study for genetic testing and SNP analysis in infants
AUTHORS:
Madalynn Neu, Marisa Ehringer, Cassandra Marcheggiani-Howard
KEYWORDS:
DNA; Infants; Temperament; Parent Consent
JOURNAL NAME:
Open Journal of Nursing,
Vol.4 No.2,
February
7,
2014
ABSTRACT: Purpose: Determine whether parents would consent to genotyping
for temperament characteristics for their infants; establish that quality DNA is
obtained from infants using a cheek swab. Design and Methods: Seventeen mother-father
dyads and infants, 11 to 35 weeks of age, who had participated in a GERD (gastroesophageal
reflux disease) massage study participated in this feasibility study. Results: Seventy-one
percent of parents agreed to genotyping. Most parents who participated were concurrently
enrolled in the GERD massage study. Reasons provided for participating were support
of research and the desire to help other families who had infants with GERD. Parents
who participated also had higher educational attainment than those who declined.
Reasons for declining were dislike of genetic research. All samples could be analyzed.
Practice Implications. Many par-ents allowed genotyping, especially if currently
engaged with research staff. Cheek swabs are a noninvasive and satisfactory method
of DNA collection.