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Rasmussen, L.S., Christiansen, M., Rasmussen, H., Kristensen, P.A. and Moller, J.T. ISPOCD Group (2000) Do blood concentrations of neurone specific enolase and S100 beta protein reflect cognitive dysfunction after abdominal surgery? British Journal of Anaesthesia, 84, 242244. http://dx.doi.org/10.1016/j.bandc.2010.05.010

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• TITLE: S100B and delirium in the geriatric acute care setting

  AUTHORS: Walaa W. Aly, Samia A. Abdul-Rahman, Salma M. S. El Said, Samah A. Bastawy

  KEYWORDS: Delirium; S100B; Elderly

  JOURNAL NAME: Advances in Aging Research, Vol.3 No.1, February 6, 2014

  ABSTRACT: Delirium and its relation to biochemical markers have been considered a study question in several research works. The relation between S100B levels and delirium is still a matter of discussion. Objective: To compare the serum level of S100B in patients with and without delirium and to detect the relation between S100B and delirium subtypes. Method: A case control study was conducted on 114 elderly (60 years and older) selected from the geriatric acute care unit at Ain Shams University Hospitals. They were classified into two groups; 58 elderly cases who had delirium diagnosed by Confusion Assessment Method and 56 controls. Then delirium was reclassified according to the subtypes of delirium into Hyperactive: 46 patients, hypoactive: 2 patients, and Mixed: 10 patients. Serum S100B levels were determined by ELISA. Results: Cases were significantly older than controls (72.4 ± 9.4 versus 66.9 ± 5.3 years respectively) (P