TITLE:
S100B and delirium in the geriatric acute care setting
AUTHORS:
Walaa W. Aly, Samia A. Abdul-Rahman, Salma M. S. El Said, Samah A. Bastawy
KEYWORDS:
Delirium; S100B; Elderly
JOURNAL NAME:
Advances in Aging Research,
Vol.3 No.1,
February
6,
2014
ABSTRACT: Delirium and its
relation to biochemical markers have been considered a study question in several research works. The relation between S100B
levels and delirium is still a matter of discussion. Objective: To compare the serum level of S100B in patients with
and without delirium and to detect the relation between S100B and delirium
subtypes. Method: A case control
study was conducted on 114 elderly (60 years and older) selected from the
geriatric acute care unit at Ain Shams University Hospitals. They were classified
into two groups; 58 elderly cases who had delirium diagnosed by Confusion
Assessment Method and 56 controls. Then delirium was reclassified according
to the subtypes of delirium into Hyperactive: 46 patients, hypoactive: 2 patients,
and Mixed: 10 patients. Serum S100B levels were determined by ELISA. Results: Cases were significantly
older than controls (72.4 ± 9.4 versus 66.9 ± 5.3 years respectively) (P