TITLE:
Vertebral Bone Drilling (Puncture) Attenuates the Acute Pain Due to Vertebral Compression Fractures
AUTHORS:
Koichi Ota, Sosi Iwasaki
KEYWORDS:
Vertebral Bone Drilling; Osteoporosis; Vertebral Compression Fractures; Acute Pain; Vertebroplasty
JOURNAL NAME:
Open Journal of Anesthesiology,
Vol.4 No.2,
January
29,
2014
ABSTRACT: Purpose: The Investigational Vertebroplasty
Efficacy and Safety Trial (INVEST), a randomized blinded controlled study of Vertebroplasty,
demonstrated similar improvements in pain between blinded Vertebroplasty and
sham-Vertebroplasty groups. The result from the RCT study suggested that the
observed efficacy of the Vertebroplasty
procedure, instead of representing the cement-mediated reduction in pain, may
relate to the vertebral bone drilling per
se. The aim of this study was to demonstrate the effectiveness of pain relief
of vertebral bone drilling at the site of painful osteoporotic vertebral
compression fractures in the acute phase. Materials and Methods: Twenty-six
patients with painful osteoporotic compression fractures underwent the
vertebral bone drilling. We assessed primary outcome measures in the NRS pain
score and RDQ score at day 0
and 3 following the drilling. Comparisons
were made by using Wilcoxon signed rank test. Results: The mean baseline NRS
and RDQ score, and the mean NRS and RDQ score at day 3 were 7.3 ± 1.2, 15.7 ±
4.2, 4.6 ± 1.4, 7.3 ± 2.2, respectively. Among the patients, we detected significant improvements in NRS pain
score and RDQ score at day 3 following the drilling compared with day 0 (P al
compression fractures alleviated the intractable pain due to osteoporotic
vertebral compression fractures.