TITLE:
Vitamin E Therapy in Non-Alcoholic Fatty Liver Disease
AUTHORS:
Xiangbing Shu, Li Zhang, Guang Ji
KEYWORDS:
Vitamin E; Nonalcoholic Fatty Liver; Therapy
JOURNAL NAME:
International Journal of Clinical Medicine,
Vol.5 No.3,
January
24,
2014
ABSTRACT: Non-alcoholic fatty liver disease (NAFLD) is
closely related to oxidative stress. Vitamin E (VE) is an effective
antioxidant, which could relieve NAFLD symptoms by improving the balance of
oxidation and anti-oxidation. However, recent researches indicate that the
functional mechanisms of VE are not only limited to anti-oxidation, but also
include adjusting the metabolism disorders of glucose and lipid. Furthermore,
the efficacy of VE remains controversial in the treatment of NAFLD by far, and
the suitable condition of patient, drug dosage, drug safety and course of treatment during clinical
application still need to be discussed. Therefore, this paper reviewed the
recent study progresses of clinical application of VE alone and VE and other drugs.