Article citationsMore>>

Punta, M., Coggill, P.C., Eberhardt, R.Y., Mistry, J., Tate, J., Boursnell, C., Pang, N., Forslund, K., Ceric, G., Clements, J, Heger, A., Holm, L., Sonnhammer, E.L.L., Eddy, S.R., Bateman, A. and Finn, R.D. (2012) The Pfam protein families database. Nucleic Acids Research, 40, D290-D301. http://dx.doi.org/10.1093/nar/gkr1065

has been cited by the following article:

• TITLE: Predicting residue contacts for protein-protein interactions by integration of multiple information

  AUTHORS: Tu Kien T. Le, Osamu Hirose, Vu Anh Tran, Thammakorn Saethang, Lan Anh T. Nguyen, Xuan Tho Dang, Duc Luu Ngo, Mamoru Kubo, Yoichi Yamada, Kenji Satou

  KEYWORDS: Residue-Residue Contacts;Domain-Domain Interactions; Protein-Protein Interactions; Domain Interfaces; Residue Co-Evolution; Contact Potentials

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.7 No.1, January 24, 2014

  ABSTRACT: Detailed knowledge of interfacial region between interacting proteins is not only helpful in annotating function for proteins, but also very important for structure-based drug design and disease treatment. However, this is one of the most difficult tasks and current methods are constrained by some factors. In this study, we developed a new method to predict residue-residue contacts of two interacting protein domains by integrating information about evolutionary couplings andamino acid pairwise contact potentials, as well as domain-domain interaction interfaces. The experimental results showed that our proposed method outperformed the previous method with the same datasets. Moreover, the method promises an improvement in the source of template-based protein docking.