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Liu, A., Hoffman, P.W., Lu, W. and Bai, G. (2004) NFkappaB site interacts with Sp factors and up-regulates the NR1 promoter during neuronal differentiation. Journal of Biological Chemistry, 279, 17449-17458.
http://dx.doi.org/10.1074/jbc.M311267200

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• TITLE: Meta-analyses of nine polymorphisms of six genes with the risk of schizophrenia

  AUTHORS: Xuting Xu, Lingyan Wang, Qi Liao, Leiting Xu, Yi Huang, Fuqiang Zhang, Jia Cheng, Meng Ye, Shugui Gao, Shiwei Duan

  KEYWORDS: Schizophrenia; Meta-Analysis; SNP

  JOURNAL NAME: Advances in Bioscience and Biotechnology, Vol.5 No.2, January 24, 2014

  ABSTRACT: The aim of this study was to determine whether 9 genetic polymorphisms confered susceptibility to schizophrenia (SCZ). The authors conducted meta-analyses on associations between SCZ and 9 variants of 6 genes including PIK3C3 (432C > T), ABCB1 (C3435T and G2677T), CTLA4 (+49A/G), OLIG2 (rs762178), GAD1 (rs1978340, rs3749034 and rs769395), and GRIN1 (G1001C). A total of 34 case-control studies were involved in our meta-analyses. Our results showed no significant association between all the loci and SCZ. This meta-analysis confirmed a lack of association of SCZ for 9 genetic polymorphisms including GRIN1 G1001C, ABCB1 C3435T and G2677T, CTLA4 + 49A/G, OLIG2 rs762178, GAD1 gene rs1978340, rs3749034 and rs769395, and PIK3C3 432C > T.