TITLE:
Feeding Study with Bt Corn (MON810: Ajeeb YG) on Rats: Biochemical Analysis and Liver Histopathology
AUTHORS:
Eman Mohamed Abdo, Omar Mohamed Barbary, Omayma El-Sayed Shaltout
KEYWORDS:
MON810: Ajeeb YG; Feeding Study; Blood Biochemical Analysis; Haematology; Histopathology
JOURNAL NAME:
Food and Nutrition Sciences,
Vol.5 No.2,
January
20,
2014
ABSTRACT: Bt corn “MON810: Ajeeb YG” produces delta endotoxins in the whole plant due to the genetic
modification process. The chemical analysis of this variety showed significant
differences from its conventional counterpart “Ajeeb”. Further, feeding studies on rats were designed to complete assessing
the safety of “MON810: Ajeeb YG”. Three groups of rats (6 males and 6 females’ rats/group) were fed on control diet, non-Bt corn and Bt corn for 1.5 months and 3 months.
After 1.5 months, 3 males and 3 females from each group
were sacrificed, and after another 1.5 months, 3 males and 3
females from each group and their offspring were sacrificed. Histopathological
examination, blood haematology and serum biochemical analysis were determined.
Results indicated significant differences among the tested parameters in the
three groups especially Bt group. Severe changes in the liver of Bt group after
3 months were observed.