TITLE:
Spontaneous and iatrogenic dehydration in the elderly alone or in combination with antiplatelet/anticoagulation agents and risk of subdural hematoma
AUTHORS:
Elizabeth Wirkowski, Jonas DeMuro, Adel Hanna, Jay Yasen, Rajiv Narain, Susan Elcin
KEYWORDS:
Subdural Hematoma; Diuretics; Aquaporins; Adverse Drug Events; Dehydration
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.4 No.1,
January
17,
2014
ABSTRACT: Background and Purpose: To evaluate the role of
preadmission conditions, dehydration specifically, in the development of
subdural hematoma in the elderly. Methods: Retrospective chart review. Results:
The most prevalent pre-admission medical condition was hypertension, followed
by atrial fibrillation, CAD, hyperlipidemia, diabetes, and cancer. Out of 95 patients,
69 (73%) had features of dehydration, 27% were on diuretics and 28% were on
antiplatelet agents and anticoagulation. Conclusions: Elderly population is
prone to dehydration. Overzealous use of diuretics especially in combination
with anticoagulation or antiplatelet therapy can contribute to the development
of subdural hematomas, both spontaneous and traumatic.