Article citationsMore>>

Hoffman, R.E., Hampson, M., Wu, K., Anderson, A.W., Gore, J.C., Buchanan, R.J., Constable, R.T., Hawkins, K.A., Sahay, N. and Krystal, J.H. (2007) Probing the pathophysiology of auditory/verbal hallucinations by combining functional magnetic resonance imaging and transcranial magnetic stimulation. Cerebral Cortex, 11, 2733-2743. http://dx.doi.org/10.1093/cercor/bhl183

has been cited by the following article:

• TITLE: Treatment of refractory auditory hallucinations in schizophrenia by rTMS: Positive impact of negative double blind controlled study

  AUTHORS: Noomane Bouaziz, Djedia Sidhoumi, Sonia Braha, Ghada Kallel, Palmyre Schenin-King Andrianisaina, Virginie Moulier, René Benadhira, Dominique Januel

  KEYWORDS: Schizophrenia; rTMS; Auditory Hallucinations; Temporo-Parietal Cortex

  JOURNAL NAME: Open Journal of Psychiatry, Vol.4 No.1, January 10, 2014

  ABSTRACT: Background: Several studies reported on the effectiveness of 1 Hz repeated transcranial magnetic stimulation (rTMS) over the temporoparietal cortex (TPC) on refractory auditory hallucinations (AH) in schizophrenia but little is known about the long-term therapeutic effect of this tool. Aim: The aim of this study was to evaluate rTMS’ impact on auditory hallucinations (AH) and cognitive functions in patients with schizophrenia with a three-month follow-up. Methods: In a randomized double blind sham controlled study, 26 patients with refractory schizophrenia received 1 Hz rTMS applied on TPC for four weeks. rTMS was given to patients over one month with five rTMS sessions each week. Patients were evaluated via AHRS (Auditory Hallucination Rating Scale, Hoffman et al.), PANSS (Positive and Negative Syndrome Scale, Kay et al. 1988), and CGI (Clinical Global Impression) before treatment by rTMS every week during the first month, and every month until the third month. Results: Neither clinical nor cognitive differences were found between rTMS and placebo. Conclusion: 1 Hz rTMS using parameters mentioned above has no statistically significant effect on AH; although evidences about the potential benefit of rTMS in the treatment of AH negative results suggest the need for further studies in this area.