TITLE:
High-Grade Mucoepidermoid Carcinoma Ex-Pleomorphic Adenoma of the Parotid Gland: Case Report and Review of Literature
AUTHORS:
Aron Z. Pollack, Benjamin C. Paul, Mike C. Sheu, Gady Har-El
KEYWORDS:
Mucoepidermoid Carcinoma; Carcinoma ex-Pleomorphic Adenoma; Pleomorphic Adenoma; Parotid Gland
JOURNAL NAME:
International Journal of Otolaryngology and Head & Neck Surgery,
Vol.3 No.1,
January
9,
2014
ABSTRACT: Background:
Mucoepidermoid carcinoma ex-pleomorphic adenoma (MECxPA) is an extremely rare
salivary gland malignancy. With only nine prior reported cases, this entity
represents a challenging histopathological diagnosis. Methods: We present a case
of a 71-year-old male with an enlarging left neck mass over several months. CT
showed both a parapharyngeal space mass and a separate level II neck mass.
Results: The patient underwent resection of the left parapharyngeal mass and
ipsilateral selective level II-IV lymphadenectomy. The final pathologic
diagnosis was metastatic high-grade mucoepidermoid carcinoma ex-pleomorphic
adenoma. Conclusions: We describe a novel presentation of high-grade
mucoepidermoid carcinoma ex-pleomorphic adenoma as a metastatic parapharyngeal
mass.