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A. T. Khan, T. Parvin and L. H. Choudhury, “A Simple and Convenient One-Pot Synthesis of Benzimidazole Derivatives Using Cobalt (II) Chloride Hexahydrate as Catalyst,” Synthetic Communications, Vol. 39, No. 13, 2009, pp. 2339-2346.

has been cited by the following article:

• TITLE: Synthesis of Multifunctionalised 2-Substituted Benzimidazoles Using Copper (II) Hydroxide as Efficient Solid Catalyst

  AUTHORS: Murugulla Adharvana Chari, Zaied-A-Mosaa, Donthabakthuni Shobha, Sridhar Malayalama

  KEYWORDS: o-Phenylenediamine; Aldehydes; Copper (II) Hydroxide; Solid Catalyst; Multifunctionalised Benzimidazoles

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.3 No.4, December 27, 2013

  ABSTRACT: Here we demonstrate the synthesis of multifunctionalised benzimidazoles through the coupling of o-phenylenediamine with aldehydes by using Copper (II) hydroxide as an efficient solid catalyst in methanol at room temperature. The Copper (II) hydroxide solid catalyst gave better yields (80%-99%) in short reaction time (4-8 h). These commercially available cheap catalysts are more active than many reported expensive heterogeneous catalysts. Using the Copper hydroxide fresh catalyst, the yield of product 3a was 98%, while the recovered catalyst in the three subsequent cycles gave the yield of 94%, 90% and 88% respectively.