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Bhakta, B., Hamuryudan, V., Brennan, P., Chamberlain, M.A., Barnes, C. and Silman, A.J. (1993) Assessment of disease activity in Behçet’s disease. In: Wechsler, B. and Godeau, P., Eds., Excerpta Medical International Congress Series 1037, 611, Elsevier Science Publishers BV, Amsterdam, 235-240.

has been cited by the following article:

• TITLE: Evaluation of a new Tunisian version of behçet’s disease current activity form*

  AUTHORS: Olfa Harzallah, Yassine Meksi, Amira Hamzaoui, Rym Klii, Amira Atig, Silvia Mahjoub

  KEYWORDS: Behçet’s Disease; Disease Activity; Disease Activity Score; Reliability of Results

  JOURNAL NAME: Open Journal of Internal Medicine, Vol.3 No.4, December 24, 2013

  ABSTRACT: Background: Behçet’s Syndrome (BS) is characterized by a heterogeneous vessel involvement, a fluctuating natural history and by the absence of biological markers correlated to disease activity that’s why objective clinical scores are needed for the assessment of its activity. The Behçet’s Disease Clinical Activity Form (BDCAF) is the most recent and widely used clinical activity score. Objectives: To perform a cross-cultural adaptation of the Behçet’s Disease Current Activity Form (BDCAF) to the Tunisian Dialect (Arabic Language) and to evaluate the metrological characteristics of the Tunisian version (Tu-BDCAF) especially its reliability in BD activity evaluation. Methods: Cross-cultural adaptation was done according to the established guidelines. Reliability of Tu-BDCAF was tested among 40 BD patients (mean age: 38 years, sex ratio: 1.37). Patients were questioned by two BD specialists at 20 minutes interval to evaluate inter-observer reproducibility and twice by the same physician at 48 hours interval to assess the intra-observer reproducibility. k Coefficient was used to test the concordance between qualitative variables and correlation between quantitative variables was evaluated used Pearson coefficient and Bland and Altman graphical method. Results: There was a good correlation between global scores calculated by the two physicians on the same day (r = 0.94, p k Coefficient analyses demonstrated a good intra and inter observer reliability for all the Tu-BDCAF items excepted for diarrhea and Clinician’s impression. As the original version, Tu-BDCAF is an objective, easy-calculated and reliable index for assessing disease activity in BD. The main limit of the BDCAF score remains the absence of a cut-off point defining BD activity. Conclusion: Tu-BDACF is a Tunisian version of the BDCAF score which can be used in routine to assess BD activity but also in international studies and clinical trials.