TITLE:
Fuzzy Cluster Analysis of Alzheimer’s Disease-Related Gene Sequences
AUTHORS:
Jing Yang, Jiarui Si, Xiaoxuan Gu, Ouyan Shi
KEYWORDS:
Alzheimer’s Disease; Gene; mRNA; Sequence; Alignment; Fuzzy Cluster
JOURNAL NAME:
Engineering,
Vol.5 No.10B,
December
20,
2013
ABSTRACT: The objective of this
paper is to analyze the relationship among the interrelated gene sequences of Alzheimer’s
disease (AD). Further this paper will provide a study on genetic factor of the occurrence
about Alzheimer’s disease, so as to provide more information on the prevention
of Alzheimer’s disease, the clinical diagnosis and gene therapy for Alzheimer’s disease. The respective
alignment of the Alzheimer’s disease interrelated gene sequences with those in
The National
Center for Biotechnology Information (NCBI) database was studied, and the measurement
relationship of these sequences was identified and analyzed by the method of
fuzzy cluster. The result of fuzzy cluster analysis indicates that the gene
sequences interrelated within one group is consistently having closer
relationship within the group other than in another group.