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J. D. Puskas, W. H. Williams, P. G. Duke, J. R. Staples, K.E. Glas, J. J. Marshall, et al., “Off-Pump Coronary Artery Bypass Grafting Provides Complete Revascularization with Reduced Myocardial Injury, Transfusion Requirements, and Length of Stay: A Prospective Randomized Comparison of Two Hundred Unselected Patients Undergoing Off-Pump versus Conventional Coronary Artery Bypass Grafting,” Journal of Thoracic and Cardiovascular Surgery, Vol. 125, No. 4, 2003, pp. 797-808. http://dx.doi.org/10.1067/mtc.2003.324

has been cited by the following article:

• TITLE: Hemodynamic Changes during Off-Pump Coronary Ar-tery Bypass Graft Surgery: Experience Using Pericardial Bands for Target Stabilization

  AUTHORS: Srikrishna Sirivella, Isaac Gielchinsky

  KEYWORDS: Circulatory Hemodynamics; CABG; New Technology; Off-Pump Surgery

  JOURNAL NAME: World Journal of Cardiovascular Surgery, Vol.3 No.8, December 16, 2013

  ABSTRACT: Background: The off-pump coronary artery bypass graft surgery (OPCAB) may produce significant hemodynamic instability necessitating conversion to on-pump surgery. This study evaluated the hemodynamic parameters in patients undergoing OPCAB using pericardial bands for stabilization of the coronary target sites. Methods: In 250 patients undergoing OPCAB the hemodynamic parameters including continuous cardiac output and systemic venous oxygen saturation (SvO2) were recorded at baseline after pericardiotomy, during each coronary artery anastomosis at 3, 5, 10, 15 min, and after release of the pericardial bands used for target stabilization. Vasopressors were used to maintain mean arterial pressure (MAP) > 60 mmHg. Results: SvO2 and cardiac index (CI) decreased significantly after target stabilization and during all coronary anastomoses with greater decreases noted during obtuse marginal branch of left circumflex (OM) anastomosis. The MAP and heart rate were maintained without significant change but central venous pressure increased significantly during all coronary anastomoses. The significant increase in pulmonary capillary wedge pressure and mean pulmonary artery pressure were noted only during anastomosis of the left anterior descending artery. The highest dose of vasopressor was used during OM anastomosis. Conclusions: During OPCAB surgery using pericardial bands for coronary target stabilization, MAP was maintained constantly, but SvO2 and CI decreased immediately after target stabilization and reduced further during all coronary artery anastomoses. During OM anastomosis SvO2 and CI were significantly lower as compared to that of LAD and right coronary artery. Careful monitoring and management of hemodynamic variables are warranted to avoid conversion to on-pump technique.